Multiple earthquakes occur all over the world where challenging fault systems exist. A structure damaged by an earthquake is exposed to the risk of aftershocks within a short interval of time, which accumulates damage to the structure affecting its stiffness, strength and ductility. This study aims to investigate the response of reinforced concrete infilled frames subjected to multiple ground motion sequences. A two dimensional computational model of a mixed used RC building located in Karachi, Pakistan is developed as a bare and infilled frames for comprehensive comparative analyses. Initially, nonlinear static pushover analysis was used to estimate the capacities and damage patterns of frames. Finally, to track the complete response selected frames were subjected to three real seismic sequences (recorded at a short interval of time at same station with same direction) and four artificially generated repeated seismic sequences. Results are presented in the form of Engineering Demand Parameters (EDPs), which conforms the effects of multiple earthquakes particularly in the case of infilled frame.
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